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In Pathogenetic Topography, we alguem know of no peculiarities in this State which are not in accordance with the usual influence of Michigan may be divided into three sections, to wit: First, the northern peninsula, favored with a climate whose salubrity renders it a profitable resort for a large class of invalids, viz., those on whom the depressing infiaences of heat and humidity have stamped that cachexia of digestive and assimilative organs, which the annual changes of the lower latitudes and especially less altitudes, so frequently aggravate to active disease, that sufficient time is not given for complete restoration to health.

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